Sabtu, 19 Juli 2008

Radiotherapy for Early Glottic Cancer

The optimal clinical scenario for using XRT in early glottic cancer is diffuse superficial disease (T1b, T2b) in which surgical intervention would disrupt the basic architecture of both vocal folds, the anterior commissure tendon, or the laminae propria.
The disadvantages of XRT include treatment of noncancerous vocal-fold tissue (T1a, T2a), which frequently results in scarring of the mucosa of the normal vocal fold with associated dysphonia (13).
DIAGNOSIS STAGING
  • Laryngeal examination and videostroboscopy
  • Panendoscopy with biopsy and mapping of the tumor
  • Computed tomography scan of the neck with contrast
  • Chest x-ray study
  • Comprehensive chemistry panel, including liver function tests
  • Complete blood count


COMPLICATIONS ON ENDOSCOPY RESECTION

  • Hemoptysis subsequent to reconstruction
  • Hematoma
  • Airway edema
  • Airway obstruction
  • Dysphonia
  • Aspiration
  • Positive surgical margins
  • Laryngeal stenosis
  • Scarring
  • Extrusion of Gore-Tex implant







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